Wearable smart sensor systems integrated on soft contact lenses forwireless ocular diagnostics

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/486986.do
DOI
10.1038/ncomms14997
Title
Wearable smart sensor systems integrated on soft contact lenses forwireless ocular diagnostics
Description
This work was supported by the Ministry of Science, ICT & FuturePlanning and the Ministry of Trade, Industry and Energy (MOTIE) of Koreathrough the National Research Foundation (2016R1A2B3013592 and2016R1A5A1009926), the Technology Innovation Program (Grant 10044410),the Nano Material Technology Development Program (2015M3A7B4050308 and2016M3A7B4910635), the Convergence Technology Development Program forBionic Arm (NRF-2014M3C1B2048198), the Pioneer Research Center Program(NRF-2014M3C1A3001208), the Human Resource Training Program for RegionalInnovation and Creativity (NRF-2014H1C1A1073051). Also, the authorsthank CooperVision Awards and financial support by the DevelopmentProgram of Manufacturing Technology for Flexible Electronics with HighPerformance (SC0970) funded by the Korea Institute of Machinery andMaterials, and by the Development Program of Internet of Nature System(1.150090.01) funded by UNIST.
abstract
Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on an actual ocular contact lens. It was also designed to monitor glucose within tears, as well as intraocular pressure using the resistance and capacitance of the electronic device. Furthermore, in-vivo and in-vitro tests using a live rabbit and bovine eyeball demonstrated its reliable operation. Our developed contact lens sensor can measure the glucose level in tear fluid and intraocular pressure simultaneously but yet independently based on different electrical responses.
provenance
Made available in Cube on 2018-09-28T16:22:13Z (GMT). No. of bitstreams: 0
language
English
author
Kim, Joohee
Kim, Minji
Lee, Mi-Sun
Kim, Kukjoo
Ji, Sangyoon
Kim, Yun-Tae
Park, Jihun
Na, Kyungmin
Bae, Kwi-Hyun
Kim, Hong Kyun
Bien, Franklin
Lee, Chang Young
Park, Jang-Ung
orcid
Park, Jang-Ung/0000-0003-1522-4958
accessioned
2018-09-28T16:22:13Z
available
2018-09-28T16:22:13Z
issued
2017
citation
NATURE COMMUNICATIONS(8)
issn
2041-1723
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/486986.do
Funder
과학기술정보통신부
Funding Program
울산과학기술원연구운영비지원(0.5)
Project ID
1711063298
Jurisdiction
Rep.of Korea
Project Name
UNIST 융합연구원 운영지원
rights
openAccess
type
article


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