Usefulness of 10-2 Matrix Frequency Doubling Technology Perimetry forDetecting Central Visual Field Defects in Preperimetric GlaucomaPatients

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/486794.do
DOI
10.1038/s41598-017-15329-1
Title
Usefulness of 10-2 Matrix Frequency Doubling Technology Perimetry forDetecting Central Visual Field Defects in Preperimetric GlaucomaPatients
abstract
It is generally acknowledged that structural loss can precede functional loss in some patients with early glaucoma. However, conventional standard automated perimetry (SAP) has limitations in the detection of functional loss, especially in the macular area. This study explores visual field loss in the macular areas of patients with preperimetric glaucoma exhibiting structural thinning in the area by examining the correlations between the ganglion cell-inner plexiform layer (GCIPL) and the results of matrix frequency-doubling technology (FDT) 10-2 tests. The structure-function relationships between the GCIPL thicknesses and the mean sensitivities (MSs) of the corresponding areas based on conventional SAP 24-2, FDT 10-2, and FDT 24-2 were examined in 62 patients. The highest correlation was found for FDT 10-2 (r = 0.544, P < 0.001) followed by FDT 24-2 (r = 0.433, P = 0.002) and SAP (r = 0.346, P = 0.007). The correlation coefficients between each GCIPL sector and the corresponding central MS according to FDT 24-2 and 10-2 were all statistically significant, and the correlations were significantly stronger for FDT 10-2 than 24-2 in the inferior and inferonasal sectors. In conclusion, preperimetric glaucoma patients with structural loss in the macula as indicated by GCIPL thinning also exhibited functional loss as revealed by FDT 10-2, and the functional loss was less evident with conventional SAP.
provenance
Made available in Cube on 2018-09-28T16:17:07Z (GMT). No. of bitstreams: 0
language
English
author
Jung, Younhea
Park, Hae-Young L.
Park, Yi Ryeung
Park, Chan Kee
accessioned
2018-09-28T16:17:07Z
available
2018-09-28T16:17:07Z
issued
2017
citation
SCIENTIFIC REPORTS(7)
issn
2045-2322
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/486794.do
Funder
교육부
Funding Program
BK21플러스사업(0.5)
Project ID
1345274430
Jurisdiction
Rep.of Korea
Project Name
BK21 PLUS Convergence HealthCare Science Program
rights
openAccess
type
article


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