Triethylammonium acetate ionic liquid assisted one-pot synthesis ofdihydropyrimidinones and evaluation of their antioxidant andantibacterial activities

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/486518.do
DOI
10.1016/j.arabjc.2014.05.007
Title
Triethylammonium acetate ionic liquid assisted one-pot synthesis ofdihydropyrimidinones and evaluation of their antioxidant andantibacterial activities
Description
We gratefully acknowledge SRC program of National Research Foundation ofKorea (NRF) Grant funded by the Korean Government (MEST) (No.20100029418) and in part by Kwangwoon University 2014. J.G. is thankfulto DST, Govt. of India, for providing financial support under theIndia-UK joint initiative project entitled "Advancing the efficiency andproduction potential of excitonic solar cells (APEX)''.
abstract
A mild and efficient catalytic method has been developed to synthesize 3,4-dihydropyrimidinones in high yield by one-pot three component Biginelli condensation in the presence of triethylammonium acetate (TEAA) which acts as catalyst/reaction medium. Further, we have studied the antioxidant and antibacterial activities of these synthesized 3,4-dihydropyrimidinones. All the synthesized compounds reveal the significant antioxidant properties, these properties have been studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and cupric reducing antioxidant capacity (CUPRAC) assays. In addition, to this, these compounds also show the good antibacterial activity against four human pathogenic bacteria. (C) 2014 King Saud University. Production and hosting by Elsevier B.V.
provenance
Made available in Cube on 2018-09-28T16:09:45Z (GMT). No. of bitstreams: 0
language
English
author
Attri, Pankaj
Bhatia, Rohit
Gaur, Jitender
Arora, Bharti
Gupta, Anjali
Kumar, Naresh
Choi, Eun Ha
orcid
gaur, jitender/0000-0001-6265-784X; Attri, Pankaj/0000-0002-5036-7877
accessioned
2018-09-28T16:09:45Z
available
2018-09-28T16:09:45Z
issued
2017
citation
ARABIAN JOURNAL OF CHEMISTRY(10): 2
issn
1878-5352
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/486518.do
Funder
미래창조과학부
Funding Program
집단연구지원
Project ID
1711042653
Jurisdiction
Rep.of Korea
Project Name
Plasma Bioscience Research Center
rights
openAccess
subject
Biginelli reaction
Ionic liquid
Triethylammonium acetate
Antioxidantactivity
Reaction medium
Antibacterial activity
type
article


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