The Role of Free Radicals in Hemolytic Toxicity Induced byAtmospheric-Pressure Plasma Jet

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/486092.do
DOI
10.1155/2017/1289041
Title
The Role of Free Radicals in Hemolytic Toxicity Induced byAtmospheric-Pressure Plasma Jet
Description
This work was financially supported by a grant from the NationalResearch Foundation of Korea (NRF), funded by the Korean government(MSIP) (NRF-2010-0027963 and NRF-NRF-2016R1A1A1A05005431).
abstract
Atmospheric-pressure plasma (APP) has received attention due to its generation of various kinds of reactive oxygen/nitrogen species (ROS/RNS). The controllability, as well as the complexity, is one of the strong points of APP in various applications. For biological applications of this novel method, the cytotoxicity should be estimated at various levels. Herein, we suggest red blood cell (RBC) as a good cell model that is simpler than nucleated cells but much more complex than other lipid model systems. Air and N-2 gases were compared to verify the main ROS/RNS in cytotoxicity, and microscopic and spectroscopic analyses were performed to estimate the damages induced on RBCs. The results shown here will provide basic information on APP-induced cytotoxicity at cellular and molecular levels.
provenance
Made available in Cube on 2018-09-28T15:58:19Z (GMT). No. of bitstreams: 0
language
English
author
Baik, Ku Youn
Huh, Yoon Ho
Kim, Yong Hee
Kim, Jeongho
Kim, Min Su
Park, Hun-Kuk
Choi, Eun Ha
Park, Byoungchoo
orcid
Choi, Eun Ha/0000-0001-5385-1878
accessioned
2018-09-28T15:58:19Z
available
2018-09-28T15:58:19Z
issued
2017
citation
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
issn
1942-0900
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/486092.do
Funder
미래창조과학부
Funding Program
집단연구지원
Project ID
1711042653
Jurisdiction
Rep.of Korea
Project Name
Plasma Bioscience Research Center
rights
openAccess
type
article


Files in This Item

There are no attached files.