Suggestion of new possibilities in approaching individual variability inappetite through constitutional typology: a pilot study

Collection with item attached
2012
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/485373.do
DOI
10.1186/1472-6882-12-122
Title
Suggestion of new possibilities in approaching individual variability inappetite through constitutional typology: a pilot study
Description
This work was supported by Kyung Hee University (Grant No.:KHU-20091665).
abstract
Background: Appetite is intricately connected to eating behaviors and shows a high individual variability. In an attempt to approach the problem of gut hormone profiles, appetite, and eating behaviors at the individual level, we have adopted a constitutional typing system widely used in traditional East-Asian medicine, the Sasang constitutional typology, in order to determine the individual variations in appetite, eating behavior, and weight change.
Methods: This pilot study was designed to investigate the variability of appetite among individuals by tracking the gut hormone patterns across different constitutional types. Pre-and post-prandial concentrations of anorectic (peptide YY (PYY), glucagon-like peptide 1 (GLP-1)) and orexigenic (active ghrelin) gut hormones were measured in healthy, normal-weight (18.5 kg/m(2) <= BMI < 23 kg/m(2)) male subjects aged 20-35 (Soyang (SY) (n = 9), Taeeum (TE) (n = 9), and Soeum (SE) (n = 10) constitutional types).
Results: Significant differences were found only in the PYY concentrations across the three groups (p = 0.031). The PYY concentration peaked at 30-min post-prandial in the SE group and was significantly higher compared to the other two groups (p = 0.004). The GLP-1 concentration peaked at 15-min post-prandial in the SE group (not significant). The ghrelin levels at 30-min pre-prandial were relatively lower in the TE group compared to the other groups (not significant).
Conclusions: In conclusion, although with weak statistical power, meaningful gut hormone patterns specific to each constitutional type were discovered in this pilot study, which could offer a new method of approaching the problem of appetite and eating behavior from the angle of individual variability in appetite.
provenance
Made available in Cube on 2018-09-28T15:39:05Z (GMT). No. of bitstreams: 0
language
English
author
Lee, Junhee
Lee, Jiwon
Shin, Hyunshang
Kim, Ki-Suk
Lee, Euiju
Koh, Byunghee
Jang, Hyeung-Jin
accessioned
2018-09-28T15:39:05Z
available
2018-09-28T15:39:05Z
issued
2012
citation
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE(12)
issn
1472-6882
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/485373.do
Funder
교육과학기술부
Funding Program
2단계연구중심대학육성(0.5)
Project ID
1345196514
Jurisdiction
Rep.of Korea
Project Name
한의과학사업단
rights
openAccess
subject
Gut hormone
Appetite
Eating behavior
Sasang constitutional typology
type
article


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