Double-ligand modulation for engineering magnetic nanoclusters

Collection with item attached
2013
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/477468.do
DOI
10.1186/1556-276X-8-104
Title
Double-ligand modulation for engineering magnetic nanoclusters
Description
This study was supported by grants from the Korea Health 21 R&D Project,Ministry of Health & Welfare, Republic of Korea (A085136), the NationalResearch Foundation of Korea (NRF) funded by the Korean government(MEST; 2011-0018360 and 2010-0019923), and the Bio & Medical TechnologyDevelopment Program of the NRF funded by the Korean government (MEST;2012050077).
abstract
Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity.
provenance
Made available in Cube on 2018-09-28T12:07:06Z (GMT). No. of bitstreams: 0
language
English
author
Kim, Bongjune
Yang, Jaemoon
Lim, Eun-Kyung
Park, Joseph
Suh, Jin-Suck
Park, Hyo Seon
Huh, Yong-Min
Haam, Seungjoo
accessioned
2018-09-28T12:07:06Z
available
2018-09-28T12:07:06Z
issued
2013
citation
NANOSCALE RESEARCH LETTERS(8)
issn
1931-7573
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/477468.do
Funder
미래창조과학부
Funding Program
리더연구자지원
Project ID
1345197333
Jurisdiction
Rep.of Korea
Project Name
Development of Gene-Scale Design, Self-Diagnosis, and Anti-Aging Technology for Structural Systems in Buildings
rights
openAccess
subject
Magnetic nanoparticle
Double-ligand modulation
Nanoemulsion
Magneticnanocluster
Magnetic resonance imaging
type
article


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