A strategy to minimize the sensing voltage drift error in a transistorbiosensor with a nanoscale sensing gate

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/474036.do
DOI
10.2147/IJN.S134441
Title
A strategy to minimize the sensing voltage drift error in a transistorbiosensor with a nanoscale sensing gate
Description
This study was supported by the Bio & Medical Technology DevelopmentProgram of the NRF funded by the Korean government MSIP(2015M3A9E2029265) and Korea Health Technology R&D Project through theKorea Health Industry Development Institute (KHIDI) funded by theMinistry of Health & Welfare, Republic of Korea (HI15C-3078-020015).
abstract
An ion-sensitive field-effect transistor ( ISFET) biosensor is thought to be the center of the next era of health diagnosis. However, questions are raised about its functions and reliability in liquid samples. Consequently, real-life clinical applications are few in number. In this study, we report a strategy to minimize the sensing signal drift error during bioanalyte detection in an ISFET biosensor. A nanoscale SnO2 thin film is used as a gate oxide layer (GOL), and the surface of the GOL is chemically modified for improving bioanalyte-specific binding and for reducing undesirable ion reactions in sample solutions. The ISFET biosensor with surface-modified GOL shows significantly reduced sensing signal error compared with an ISFET with bare GOL in both diluted and undiluted phosphate buffered saline solutions.
provenance
Made available in Cube on 2018-09-28T10:35:31Z (GMT). No. of bitstreams: 0
language
English
author
Son, Hyun Woo
Jeun, Minhong
Choi, Jaewon
Lee, Kwan Hyi
orcid
Lee, Kwan Hyi/0000-0002-7891-844X
accessioned
2018-09-28T10:35:31Z
available
2018-09-28T10:35:31Z
issued
2017
citation
INTERNATIONAL JOURNAL OF NANOMEDICINE(12)
issn
1178-2013
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/474036.do
Funder
보건복지부
Funding Program
임상연구인프라조성
Project ID
1465024682
Jurisdiction
Rep.of Korea
Project Name
Electric and Magnetic Field Effect Biosensors to Detect CCSP for Early Diagnosis of Colorectal Cancer
rights
openAccess
subject
extended gate
surface treatment
biosensor
SnO2
ISFET
type
article


Files in This Item

There are no attached files.