A Quantitative Electroencephalography Study on Cochlear Implant-InducedCortical Changes in Single-Sided Deafness with Tinnitus

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/473935.do
DOI
10.3389/fnhum.2017.00210
Title
A Quantitative Electroencephalography Study on Cochlear Implant-InducedCortical Changes in Single-Sided Deafness with Tinnitus
Description
This work was supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government (MSIP) (No. 2016R1C1B2007911)and Institute for Information and communications Technology Promotion(IITP) grant funded by the Korea government (MSIP; 2014-0-00065,Resilient Cyber-Physical Systems Research)(http://www.nrf.re.kr/nrf_eng_cms/).
abstract
The mechanism of tinnitus suppression after cochlear implantation (CI) in single-sided deafness (SSD) is not fully understood. In this regard, by comparing pre-and post-CI quantitative electroencephalography (qEEG), we explored cortical changes relevant to tinnitus improvement. In SSD patients who underwent CI, qEEG data were collected: (1) before CI, (2) 6 months post-operatively with CI-on, and (3) 30 min after CI-off and source-localized cortical activity/functional connectivity analyses were performed. Compared to the pre-operative baseline, the CI-on condition demonstrated significantly decreased activity in the right auditory-and orbitofrontal cortices (OFC) for the delta frequency band as well as decreased connectivity between the auditory cortex/posterior cingulate cortex for the delta/beta2 bands. Meanwhile, compared to the CI-off condition, the CI-on condition displayed decreased activity in the right auditory cortices/OFC for the delta band, and in bilateral auditory cortices, left inferior frontal cortex/OFC for the gamma band. However, qEEG analyses showed no significant differences between the CI-off and baseline conditions. CI induced overall decreased cortical activity and functional connectivity. However, judging from no differences between the CI-off and baseline conditions, CI-induced cortical activity and functional connectivity changes are not by cortical plastic changes, but by dynamic peripheral reafferentation.
provenance
Made available in Cube on 2018-09-28T10:32:49Z (GMT). No. of bitstreams: 0
language
English
author
Song, Jae-Jin
Kim, Kyungsoo
Sunwoo, Woongsang
Mertens, Griet
Van de Heyning, Paul
De Ridder, Dirk
Vanneste, Sven
Lee, Sang-Youp
Park, Kyung-Joon
Choi, Hongsoo
Choi, Ji-Woong
orcid
Song, Jae-Jin/0000-0002-6631-3232
accessioned
2018-09-28T10:32:49Z
available
2018-09-28T10:32:49Z
issued
2017
citation
FRONTIERS IN HUMAN NEUROSCIENCE(11)
issn
1662-5161
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/473935.do
Funder
과학기술정보통신부
Funding Program
SW컴퓨팅산업원천기술개발
Project ID
1711055633
Jurisdiction
Rep.of Korea
Project Name
Resilient Cyber-Physical Systems Research
rights
openAccess
subject
single side deafness
tinnitus
cochlear implantation
electroencephalography
dynamic peripheral reafferentation
type
article


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