A primary pure pancreatic-type acinar cell carcinoma of the stomach: acase report

Collection with item attached
2017
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/473919.do
DOI
10.1186/s13000-017-0601-z
Title
A primary pure pancreatic-type acinar cell carcinoma of the stomach: acase report
Description
This work was supported by a National Research Foundation of Korea (NRF)grant funded by the Korea government (MSIP) (No. 2008-0062279).
abstract
Background: Acinar cell carcinoma represents only 1-2% of exocrine pancreatic neoplasms. On exceptionally rare occasions, primary acinar cell carcinoma can occur in ectopic locations. Herein, we report a case of pure pancreatic-type acinar cell carcinoma arising in the stomach.
Case presentation: A 54-year-old male presented with a gastric submucosal mass detected by endoscopic examination. Laparoscopic wedge resection was performed. Macroscopically, the 2.7 cm yellowish mass was located in the submucosa of the stomach. Microscopically, the tumor was well circumscribed and had a homogeneous acinar architecture. The tumor cells were small and had a minimal amount of cytoplasm. The nuclei of the tumor cells were round to oval with finely dispersed chromatin. The tumor cells were strongly positive for alpha 1-antitrypsin, chymotrypsin, and alpha 1-antichymotrypsin immunostaining, consistent with pancreatic exocrine differentiation. There was no clinical or radiologic evidence of primary pancreatic or head and neck tumors. After surgical resection of the tumor, there was no recurrence or metastasis during 33 months follow-up.
Conclusion: In this report, we have presented a rare case of primary pure pancreatic-type acinar cell carcinoma arising in the stomach and suggest that it could be helpful if the pathologist were aware that pancreatic-type acinar cell carcinoma could arise in the stomach as a polypoid submucosal tumor in the routine diagnostic field of gastric endoscopy.
provenance
Made available in Cube on 2018-09-28T10:32:23Z (GMT). No. of bitstreams: 0
language
English
author
Kim, Kyoung Min
Kim, Chan Young
Hong, Seung-Mo
Jang, Kyu Yun
accessioned
2018-09-28T10:32:23Z
available
2018-09-28T10:32:23Z
issued
2017
citation
Diagnostic Pathology(12)
issn
1746-1596
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/473919.do
Funder
교육부
Funding Program
BK21플러스사업(0.5)
Project ID
1345274062
Jurisdiction
Rep.of Korea
Project Name
The Translational Research Education Program for 21st Century
rights
openAccess
subject
Acinar cell carcinoma
Heterotopic pancreas
Stomach
type
article


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