A carcinogenic potency database of the standardized results of animal bioassays

Collection with item attached
1984_12
Item details URL
http://open-repository.kisti.re.kr/cube/handle/open_repository/446589.do
Title
A carcinogenic potency database of the standardized results of animal bioassays
Description
The preceding paper described our numerical index of carcinogenic potency, the TD50 and the statistical procedures adopted for estimating it from experimental data. This paper presents the Carcinogenic Potency Database, which includes results of about 3000 long-term, chronic experiments of 770 test compounds. Part II is a discussion of the sources of our data, the rationale for the inclusion of particular experiments and particular target sites, and the conventions adopted in summarizing the literature. Part III is a guide to the plot of results presented in Part IV. A number of appendices are provided to facilitate use of the database. The plot includes information about chronic cancer tests in mammals, such as dose and other aspects of experimental protocol, histopathology and tumor incidence, TD50 and its statistical significance, dose response, author's opinion and literature reference. The plot readily permits comparisons of carcinogenic potency and many other aspects of cancer tests; it also provides quantitative information about negative tests. The range of carcinogenic potency is over 10 million-fold.
provenance
Made available in Cube on 2016-05-29T04:25:25Z (GMT). No. of bitstreams: 0
language
en
creator
Gold, Lois Swirsky
Sawyer, Charles B.
Magaw, Renae
Backman, Georganne M.
De Veciana, Margarita
Levinson, Robert
Hooper, N. Kim
Havender, William R.
Bernstein, Leslie
Peto, Richard
Pike, Malcolm C.
Ames, Bruce N.
date
1984-12
accessioned
2016-05-29T04:25:25Z
available
2016-05-29T04:25:25Z
issued
2016-05-29
identifier
/pmc/articles/PMC1569423/
/pubmed/6525996
uri
http://open-repository.kisti.re.kr/cube/handle/open_repository/446589.do
rights
subject
Articles
type
Text


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